CD27 anticorps (AA 20-191) (Biotin)
Aperçu rapide pour CD27 anticorps (AA 20-191) (Biotin) (ABIN7093003)
Antigène
Voir toutes CD27 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 20-191
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Purification
- Purified from cell culture supernatant by affinity chromatography
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Immunogène
- Recombinant human CD27 (Ala20-Arg191) (ABIN6961160) produced by using human HEK293 cells
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Isotype
- IgG
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Indications d'application
- ELISA 1/5000-10000,Flow Cyt 1/100
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Reconstitute with deionized water
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Buffer
- 50 % Glycerol, PBS, pH 7.4, 0.1 % BSA,0.1 % Procline 300
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
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Date de péremption
- 12 months
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- CD27 (CD27 Molecule (CD27))
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Autre désignation
- CD27
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Sujet
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Synonyms:CD27, TNFRSF7, S152, T14, Tp55
Description:The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor. -
Poids moléculaire
- 29 kDa
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ID gène
- 939
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UniProt
- P26842
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Pathways
- Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
Antigène
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